Scenarios for Phase 1 Lenacapavir roll-out: Impact 2026–2030

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Infections Averted

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Combination close to health department's roll-out plan

Highest-impact scenario from modelled data

Sources: Jamieson, L. et al. Lenacapavir: Impact and cost-effectiveness of scale-up for South Africa’s HIV response, presentation at Sanac/National Department of Health lenacapavir roundtable, 14 October 2025